Mitochondria — the cellular powerhouse behind red light technology
Science & Research

The Science of Red Light for Professionals.

Find the published research most relevant to your wellness business. Curated by application area and grouped by the kind of space you run.

3
Wellness business types
34
Studies curated below
Decades
Of published red light research

Explore the published research most relevant to your wellness business. Every study below is sourced from published journals — not MedWave-funded research.

A note on how to read this page: the research below is about red and near-infrared light in general. It was not conducted on MedWave devices, it does not describe results any individual should expect, and some of it is laboratory or mechanism research rather than studies in people. It is published here so you can read the source material and reach your own view.

Browse by Business Type.

Choose the kind of space you run to find the studies that matter most to your clients.

Research relevant to day spas, beauty salons, and skin studios — covering skin appearance, tone and glow, and graceful aging.

5 studies

Unlocking the Power of Light on the Skin: A Comprehensive Review (2024)

A narrative review of recent research on red and near-infrared light and the skin, covering the proposed mechanisms at cell level and how light sources and session protocols are developing.

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Red and Near-Infrared Light and Skin Appearance: A Controlled Trial (Wunsch & Matuschka, 2014)

136 volunteers took part in this randomized, controlled study. After 30 sessions, the groups receiving light showed improvements in skin complexion, measured skin roughness and ultrasound-measured collagen density compared with the control group.

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LED Light and Skin Rejuvenation: A Randomized, Split-Face Study (Lee et al., 2007)

76 adults with facial wrinkles received 633nm, 830nm, combined or sham LED light twice a week for four weeks. The light groups showed measured reductions in wrinkles and increases in skin elasticity compared with baseline.

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Red-Light Photons on Skin Cells and the Mechanism of Photobiomodulation (2024)

Explores the cellular mechanisms by which red-light photons interact with skin cells, and what happens next inside the cell.

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Metabolic Effects of Whole-Body Vibration (Milanese et al., 2018)

In 22 physically active young men, a 20-minute whole-body vibration session raised oxygen consumption by about 22% and estimated energy expenditure by about 20% compared with the same exercises without vibration.

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Research for gym owners, coaches, and fitness professionals — covering pre-workout readiness, muscle performance, fatigue and recovery after exercise.

7 studies

Photobiomodulation in Human Muscle Tissue: An Advantage in Sports Performance? (Ferraresi et al., 2016)

A review of 46 studies (1,045 participants) of red and near-infrared light in trained and untrained volunteers and athletes, looking at muscle performance, fatigue and post-exercise recovery.

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Light Before a Sprint Test in High-Level Rugby Players: Double-Blind Study (Pinto et al., 2016)

Randomized, placebo-controlled crossover trial in 12 high-level male rugby players. Light applied before a sprint test (laser and LED, 640–905nm) improved average sprint time and fatigue index compared with placebo.

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Light for Muscular Performance and Fatigue in Healthy People: Systematic Review (Vanin et al., 2018)

Systematic review and meta-analysis of 39 randomized trials (861 participants) of light used around exercise in healthy people. It reports some effect in favor of light on time to exhaustion, repetitions and peak torque, with very low to moderate quality of evidence.

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Infrared Light Before an Intense Running Test in High-Level Soccer Players (Tomazoni et al., 2019)

Randomized, triple-blind, placebo-controlled crossover trial in 22 high-level male soccer players, looking at infrared light applied before a progressive running test and measures including VO2 max and time to exhaustion.

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Photobiomodulation and Sports: Results of a Narrative Review (Ailioaie & Litscher, 2021)

A narrative review of research published since 2014 on red and near-infrared light in sport, covering performance and recovery across 39 human studies and the reasons some studies found no effect.

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Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation (Hamblin, 2018)

A review of how red and near-infrared light is absorbed in the mitochondria and the cell signaling that follows, including how light may interact with exercise in muscle.

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Metabolic Effects of Whole-Body Vibration (Milanese et al., 2018)

In 22 physically active young men, a 20-minute whole-body vibration session raised oxygen consumption by about 22% and estimated energy expenditure by about 20% compared with the same exercises without vibration.

Read the study →

A broad overview of the science behind red light technology for wellness spaces, massage and bodywork studios — covering the core mechanisms, sleep and relaxation, and whole-body vibration.

4 studies

Proposed Mechanisms of Photobiomodulation (de Freitas & Hamblin, 2016)

A review of how red and near-infrared light is thought to work: light absorbed by cytochrome c oxidase in the mitochondria is proposed to release inhibitory nitric oxide, increasing electron transport and ATP production.

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Metabolic Effects of Whole-Body Vibration (Milanese et al., 2018)

In 22 physically active young men, a 20-minute whole-body vibration session raised oxygen consumption by about 22% and estimated energy expenditure by about 20% compared with the same exercises without vibration.

Read the study →

Light Buckets and Laser Beams: Mechanisms and Applications of Photobiomodulation (Frankowski et al., 2025)

A review of a National Institute on Aging workshop, covering the proposed mechanisms of red and near-infrared light and the research directions discussed by the scientists taking part.

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Lights at Night: Does Photobiomodulation Improve Sleep? (Valverde et al., 2023)

A short review exploring red and near-infrared light and sleep quality, including animal research on how the brain clears fluid and waste products at night.

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Watch & Learn.

Documentaries, science deep dives, and expert discussions exploring red light technology across wellness applications.

Red Light Therapy for Sports Recovery & Muscle Comfort

MedWave Documentary — how red light technology is changing post-exercise recovery and everyday muscle comfort.

Light is Life

MedWave Documentary — the story of red light and its impact on everyday wellness.

MedWave Step-by-Step Routine

A practical walkthrough of the MedWave session routine, start to finish.

Wellness Professional Roundtable with Dr Coertzen

Smart Talk — a discussion on building red light sessions into a wellness business.

Wellness Professional Roundtable with Tania Vos

Smart Talk — insights on client results and fitting red light into a busy studio.

Mental Clarity & Red Light Technology

Red light’s role in supporting focus, mental clarity, and relaxation.

Red Light for Sports & Muscle Recovery

How red light supports recovery after exercise and activity.

The MedWave System Walkthrough

A complete walkthrough of the MedWave system and how wellness businesses are building red light sessions into their offering.

US PatentedDelivered by MedWave’s US patented panel design. U.S. Patent No. 12,766,335 B2.

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© 2026 MedWave Group. U.S. Patent No. 12,766,335 B2.
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MedWave devices are general wellness products. They are not medical devices and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. Individual experiences are personal to the people describing them and are not a promise of any particular result. The information provided on this website is for educational and informational purposes only and does not constitute medical advice. Always consult with a licensed healthcare provider regarding any medical concerns or before starting any new treatment or wellness program.
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